Linear amyopathic dermatomyositis with calcinosis cutis responsive to topical sodium thiosulfate

Pediatr Dermatol. 2019 Jul;36(4):e102-e103. doi: 10.1111/pde.13868. Epub 2019 May 28.

Abstract

A case of a 15-year-old male patient with a 3-year history of linear, segmental amyopathic dermatomyositis with calcinosis cutis is presented. The calcinosis was recalcitrant to treatment with topical steroids and hydroxychloroquine. Topical 10% sodium thiosulfate use for 8 weeks resulted in improvement. The use of topical sodium thiosulfate for patients in whom surgical extraction is not an option is detailed.

Keywords: connective tissue disorders; lumps/bumps; therapy -topical.

Publication types

  • Case Reports

MeSH terms

  • Administration, Topical
  • Adolescent
  • Biopsy, Needle
  • Calcinosis / complications
  • Calcinosis / diagnosis*
  • Chronic Disease
  • Dermatomyositis / complications
  • Dermatomyositis / diagnosis
  • Dermatomyositis / drug therapy*
  • Dermatomyositis / pathology*
  • Humans
  • Immunohistochemistry
  • Leg Dermatoses / diagnosis
  • Leg Dermatoses / etiology
  • Male
  • Skin Diseases / drug therapy
  • Skin Diseases / pathology
  • Thiosulfates / therapeutic use*
  • Treatment Outcome

Substances

  • Thiosulfates
  • sodium thiosulfate

Supplementary concepts

  • Amyopathic dermatomyositis