Mouse microbiomes: overlooked culprits of experimental variability

Genome Biol. 2019 May 29;20(1):108. doi: 10.1186/s13059-019-1723-2.


Recent studies have found differences between almost genetically identical mice that were attributable to differences between their microbiomes. One example of mice from different vendors having different susceptibilities to infection by Salmonella enterica serovar Typhimurium has just been published in Nature Microbiology.

Publication types

  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Animals
  • Enterobacteriaceae
  • Mice
  • Microbiota*
  • Salmonella Infections, Animal*
  • Salmonella typhimurium