Onycholysis an early indicator of thyroid disease

Pan Afr Med J. 2019 Jan 17:32:31. doi: 10.11604/pamj.2019.32.31.17653. eCollection 2019.


Onycholysis is also referred to plummer's nails is a dermatological nail disorder characterized by spontaneous distal separation of the nail plate from the free margin and progressively proximally. We discuss a case of the 38-year-old man with onycholysis associated with hyperthyroidism due to Graves' disease. In this case review, we will discuss an association of onycholysis with thyroid disease and its diagnostic prognosis. Any unexplained onycholysis should prompt the clinician to investigate the client for asymptomatic hyperthyroidism.

Keywords: Graves´ disease; Onycholysis; hyperthyroidism; hypothyroidism; plummer´s nails; thyroid disease.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Graves Disease / complications
  • Graves Disease / diagnosis*
  • Humans
  • Hyperthyroidism / complications
  • Hyperthyroidism / diagnosis*
  • Male
  • Onycholysis / diagnosis
  • Onycholysis / etiology*
  • Prognosis