Binding or Hydrolysis? How Does the Strigolactone Receptor Work?

Trends Plant Sci. 2019 Jul;24(7):571-574. doi: 10.1016/j.tplants.2019.05.001. Epub 2019 May 28.


The strigolactone (SL) receptor in plants is unusual in that it both binds and hydrolyses SL molecules. Landmark studies had proposed that a product of hydrolysis irreversibly binds the receptor and then activates signalling. However, recent breakthrough articles (Seto et al. Nat. Commun. 2019;10:191 and Shabek et al. Nature 2018;563:652-656) have revealed a new model based on inhibition of hydrolysis by protein conformation.

Keywords: D14; hydrolysis; receptor; signal perception; signalling; strigolactone.

Publication types

  • Comment

MeSH terms

  • Hydrolysis
  • Lactones
  • Ligases
  • Plant Growth Regulators*
  • Plant Proteins
  • Ubiquitin*


  • Lactones
  • Plant Growth Regulators
  • Plant Proteins
  • Ubiquitin
  • Ligases