SwissPalm 2: Protein S-Palmitoylation Database

Abstract

Protein S-palmitoylation is increasingly recognized as an important posttranslational modification, present in all eukaryotic organisms, involved in the regulation of many biological processes. The SwissPalm database centralizes the large and increasing number of published palmitoyl-proteome datasets, provides tools to compare them, and includes curated data from the literature on the identification and analysis of palmitoylated proteins. SwissPalm 2 provides an updated version, with 38 palmitoyl-proteomes at the time of release, from 17 different species, and new features such as the inclusion of orthologs.

Keywords: Confidence; DHHC; Database; Palmitoyl-proteomes; Palmitoylation; Posttranslational modification; Proteomics; S-acylation.