Abnormally increased vocal responses to pitch feedback perturbations in patients with cerebellar degeneration

J Acoust Soc Am. 2019 May;145(5):EL372. doi: 10.1121/1.5100910.


Cerebellar degeneration (CD) has deleterious effects on speech motor behavior. Recently, a dissociation between feedback and feedforward control of speaking was observed in CD: Whereas CD patients exhibited reduced adaptation across trials to consistent formant feedback alterations, they showed enhanced within-trial compensation for unpredictable formant feedback perturbations. In this study, it was found that CD patients exhibit abnormally increased within-trial vocal compensation responses to unpredictable pitch feedback perturbations. Taken together with recent findings, the results indicate that CD is associated with a general hypersensitivity to auditory feedback during speaking.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Acoustic Stimulation / methods
  • Adult
  • Feedback
  • Feedback, Sensory / physiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pitch Perception / physiology*
  • Speech / physiology*
  • Speech Perception / physiology
  • Voice / physiology*