Heart and lung transplantation in patients with end stage lung disease

Br Med J (Clin Res Ed). 1987 Aug 1;295(6593):311-4. doi: 10.1136/bmj.295.6593.311.


Combined heart and lung transplantation was used to treat seven patients with end stage lung disease. All were severely disabled, and their disease carried a poor prognosis. Six patients were well four to 33 months after transplantation. One patient died after 44 days from a primary cytomegalovirus pneumonia transmitted from the donor. All the survivors had normal exercise tolerance and greatly improved lung function. It is concluded that heart and lung transplantation is a suitable treatment for selected patients with end stage chronic lung disease.

MeSH terms

  • Adult
  • Chronic Disease
  • Female
  • Forced Expiratory Volume
  • Heart / physiopathology
  • Heart Transplantation*
  • Heart-Lung Transplantation*
  • Humans
  • Lung / physiopathology
  • Lung Diseases / physiopathology
  • Lung Diseases / surgery*
  • Lung Transplantation*
  • Male
  • Middle Aged
  • Postoperative Complications
  • Prognosis