Introduction: Infertility etiology and offspring health

Fertil Steril. 2019 Jun;111(6):1033-1035. doi: 10.1016/j.fertnstert.2019.04.043.


This issue's of Views and Reviews considers the origins of lifetime health established around the time of conception in some prevalent conditions related to infertility. Reviews will look at the effects of advanced paternal and maternal age, the influence of the severe sperm factor, and the impact of some endocrinopathies commonly seen in infertile couples, especially women, like polycystic ovary syndrome, under- and overweight, diabetes, and thyroid disorders. The aim of this Views and Reviews section is to summarize current evidence on the consequences of these conditions on postnatal health to encourage research in this field and the need to develop strategies and preventative measures to reduce or prevent unfavorable outcomes in future generations.

Keywords: Infertility; developmental origins of health and disease; offspring health; parental health.

Publication types

  • Introductory Journal Article

MeSH terms

  • Adolescent
  • Child
  • Child Health*
  • Child of Impaired Parents*
  • Child, Preschool
  • Disease Susceptibility
  • Female
  • Fertility*
  • Health Status
  • Humans
  • Infant
  • Infant, Newborn
  • Infertility, Female / etiology*
  • Infertility, Female / physiopathology
  • Infertility, Female / therapy
  • Infertility, Male / etiology*
  • Infertility, Male / physiopathology
  • Infertility, Male / therapy
  • Male
  • Maternal Age
  • Maternal Health
  • Paternal Age
  • Reproductive Techniques, Assisted
  • Risk Assessment
  • Risk Factors
  • Treatment Outcome