Does Bupropion Impact More than Mood? A Case Report and Review of the Literature

Cureus. 2019 Mar 19;11(3):e4277. doi: 10.7759/cureus.4277.


Sexual side effects are often an unintended consequence of antidepressant treatment. Given antidepressants of different classes are frequently paired together in order to improve therapeutic response, understanding their interplay in regards to sexual functioning is important. Bupropion is an atypical antidepressant which is often used as a Selective Serotonin Reuptake Inhibitors adjunct in the treatment of depression, as well as in the amelioration of decreased libido. The following case highlights the importance of understanding antidepressant medications and their combined potential effect on sexual function to prevent unnecessary complications in cases involving the history of paraphilic disorders and hypersexuality.

Keywords: bupropion; hypersexuality disorder; selective serotonin reuptake inhibitors (ssri).

Publication types

  • Case Reports