Multidrug- and colistin-resistant Salmonella enterica 4,[5],12:i:- sequence type 34 carrying the mcr-3.1 gene on the IncHI2 plasmid recovered from a human

J Med Microbiol. 2019 Jul;68(7):986-990. doi: 10.1099/jmm.0.001012. Epub 2019 Jun 4.

Abstract

A colistin-resistant Salmonella enterica 4, [5],12:i:- sequence type (ST) 34 harbouring mcr-3.1 was recovered from a patient who travelled to China 2 weeks prior to diarrhoea onset. Genomic analysis revealed the presence of the mcr-3.1 gene located in the globally disseminated IncHI2 plasmid, highlighting the intercontinental dissemination of the colistin-resistant S. enterica 4, [5],12:i:- ST34 pandemic clone.

Keywords: 12:i:-; IncHI2; MCR-3.1; Salmonella enterica 4; United States; [5].

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism*
  • China
  • Drug Resistance, Multiple, Bacterial / genetics*
  • Humans
  • Plasmids / genetics*
  • Salmonella enterica / drug effects*
  • Salmonella enterica / genetics
  • Salmonella enterica / isolation & purification
  • Transferases (Other Substituted Phosphate Groups) / genetics
  • Transferases (Other Substituted Phosphate Groups) / metabolism*
  • Travel

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Transferases (Other Substituted Phosphate Groups)