Epidemiological and Clinical Characteristics of Confirmed Cases of Severe Fever With Thrombocytopenia Syndrome in Jeju Province, Korea, 2014-2018

J Prev Med Public Health. 2019 May;52(3):195-199. doi: 10.3961/jpmph.18.289. Epub 2019 Apr 3.

Abstract

Objectives: Jeju Province is well known as the region showing the highest incidence of severe fever with thrombocytopenia syndrome (SFTS) in South Korea. The aim of this study was to evaluate the epidemiological and clinical characteristics of SFTS patients in Jeju Province.

Methods: The primary data for this study were obtained from the Integrated Diseases and Health Control System of the Korea Centers for Disease Control and Prevention (KCDCIS). The selection criteria were confirmed cases of SFTS with a residence listed in Jeju Province at the time of diagnosis, reported to the KCDCIS between July 16, 2014 and November 30, 2018.

Results: Of 55 confirmed cases of SFTS, the case fatality rate was 10.9% (95% confidence interval [CI], 4.1 to 22.2). The most common presenting symptoms at diagnosis of severe fever, myalgia, and diarrhea had incidences of 83.6% (95% Cl, 71.2 to 92.2), 45.5% (95% Cl, 32.0 to 59.5), and 40.0% (95% CI, 27.0 to 54.1), respectively.

Conclusions: Compared to SFTS patients nationwide in 2013-2015, the subjects of this study exhibited a lower case fatality rate and had a lower incidence of severe fever, myalgia, and confusion.

Keywords: Bunyaviridae infections; Diarrhea; Thrombocytopenia; Tick-borne diseases.

MeSH terms

  • Adult
  • Aged
  • Animals
  • Bunyaviridae Infections / diagnosis*
  • Bunyaviridae Infections / epidemiology
  • Female
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Phlebovirus / pathogenicity*
  • Republic of Korea / epidemiology
  • Tick-Borne Diseases / diagnosis
  • Tick-Borne Diseases / epidemiology
  • Ticks