Socioeconomic impact of Hodgkin lymphoma in adult patients: a systematic literature review

Leuk Lymphoma. 2019 Dec;60(13):3116-3131. doi: 10.1080/10428194.2019.1613538. Epub 2019 Jun 6.

Abstract

Hodgkin lymphoma is a highly curable disease with a peak incidence in young adulthood at times where education, family, and social relations are established. We performed a systematic literature review to assess the impact of Hodgkin lymphoma on the socioeconomic status of adolescent and adult survivors (including educational achievements, occupational aspects, marriage, and parenthood). In total, 39 articles were included. Overall, 26-36% of survivors perceived Hodgkin lymphoma as negatively affecting their socioeconomic status. Studies consistently found educational achievements in line with general population. Employment rates for survivors were comparable to the general population, but lower than before Hodgkin lymphoma diagnosis, with a post-diagnosis increase in disability pension and early retirement. Employed survivors encountered problems related to physical restrictions and recruitment. Marriage and parenthood were not substantially affected. In conclusion, current studies suggest acceptable socioeconomic outcomes following a Hodgkin lymphoma diagnosis but the use of standardized reporting methods hampers comparability across studies.

Keywords: Hodgkin lymphoma; fertility; late complications; socioeconomic impact; survivorship.

Publication types

  • Systematic Review

MeSH terms

  • Adolescent
  • Adult
  • Cancer Survivors
  • Cost of Illness*
  • Disabled Persons / statistics & numerical data*
  • Educational Status
  • Employment / economics
  • Employment / statistics & numerical data
  • Hodgkin Disease / economics*
  • Hodgkin Disease / mortality
  • Hodgkin Disease / psychology
  • Humans
  • Marital Status / statistics & numerical data
  • Parents
  • Quality of Life / psychology*
  • Social Class*
  • Young Adult