Vitamin C in Cancer Therapeutics and Metastasis

J Orthop Res Ther. 2019;10(1):1127. doi: 10.29011/2575-8241.001127. Epub 2019 Jan 31.


There have been significant increased publications of preclinical studies and clinical trials of vitamin C (ascorbate) on cancer therapeutics in the past a few years. In this communication reflecting my personal opinions, I will highlight the main points of current research status; discuss impacts of vitamin C on immune cell function and inflammation at tumor microenvironment, and tumor metastasis; and propose stimulating questions and direction for future research in this area.