Triterpenoids and steroids from the fruiting bodies of Hexagonia tenuis and their cytotoxicity

Nat Prod Res. 2021 Jan;35(2):251-256. doi: 10.1080/14786419.2019.1624963. Epub 2019 Jun 10.


One new triterpenoid, hexagonin F (1) was characterized from the fruiting bodies of Hexagonia tenuis with the assistance of spectroscopic and spectrometric analytical methods. In addition, two triterpenoids and two steroids were also identified by comparison of their physical and spectroscopic data with those reported. The purified compounds were examined for their cytotoxicity against five tumor cell lines, however, only weak cytotoxicity was demonstrated.

Keywords: Hexagonia tenuis; fruiting body; spectroscopic and spectrometric analysis; steroid; triterpenoid.

MeSH terms

  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology
  • Cell Line, Tumor
  • Drug Screening Assays, Antitumor
  • Fruiting Bodies, Fungal / chemistry
  • Hep G2 Cells
  • Humans
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Polyporaceae / chemistry*
  • Spectrometry, Mass, Electrospray Ionization
  • Steroids / chemistry*
  • Steroids / pharmacology*
  • Triterpenes / chemistry*
  • Triterpenes / pharmacology*
  • Vietnam


  • Antineoplastic Agents
  • Steroids
  • Triterpenes

Supplementary concepts

  • Hexagonia tenuis