Repair of partial atrioventricular canal defect in adult patients: two-year follow-up outcomes of a retrospective study

J Cardiothorac Surg. 2019 Jun 11;14(1):106. doi: 10.1186/s13019-019-0931-x.


Background: Partial atrioventricular canal defects (PAVC) are preferred to be repaired when diagnosed and before an operation would interfere with school. There were rare previous studies about partial atrioventricular canal defect operations in adult patients. In this single-center retrospective study, we mean to review the mid-term follow-up outcomes of late diagnosed and repaired partial atrioventricular canal defects in adult patients.

Methods: 46 adult partial atrioventricular canal defect patients who underwent operation in West China Medical Center from 2009 to 2017 were included. Required data were obtained from operation notes, patient charts and the outpatient records.

Results: Among 46 patients, 10(21.7%)were male and mean age at operation was 37.6 ± 12.4 years. 11 patients had prior arrythmia, including 8 atrial fibrillations, 2 atrioventricular blocks and 1 left bundle branch block. There were 41 patients with tricuspid valve regurgitation and 22 underwent tricuspid valvuloplasty. All the patients had mitral regurgitation. 6 patients with valve incrassation and shrinkage underwent mitral valve replacement, and the rest underwent mitral repair surgery. There was one early death post operation and no more mortalities in the following follow-up years. According to the follow-up outcomes, heart function of the patients recovered significantly, dilation of atriums and ventricles, except for left atriums, were reversed to a large extent and all but one patients' tricuspid valve regurgitations were reduced to mild and below. 4(8.7%) patients underwent reoperation and the main reasons were arrythmia and recurrent severe mitral valve regurgitation.

Conclusion: Partial atrioventricular canal defect repair in adult patients can achieve good results. Compared with the results of patients underwent operations in preschool years, though delayed surgery timing seems to bring more preoperative complications and influences heart function, the mortality and reoperation rate are excellent.

Keywords: Cardiovascular surgery; Congenital heart disease; Partial atrioventricular canal defect; Partial atrioventricular septal defect; Retrospective study.

MeSH terms

  • Adult
  • Arrhythmias, Cardiac / complications
  • Cardiac Surgical Procedures / adverse effects
  • China
  • Delayed Diagnosis
  • Female
  • Follow-Up Studies
  • Heart Septal Defects, Ventricular / complications
  • Heart Septal Defects, Ventricular / diagnosis
  • Heart Septal Defects, Ventricular / surgery*
  • Humans
  • Male
  • Middle Aged
  • Mitral Valve Insufficiency / complications
  • Mitral Valve Insufficiency / surgery
  • Postoperative Complications
  • Reoperation
  • Retrospective Studies
  • Tricuspid Valve Insufficiency / complications
  • Tricuspid Valve Insufficiency / surgery

Supplementary concepts

  • Partial atrioventricular canal