Pulmonary hypertension and right ventricular remodeling in HFpEF and HFrEF

Heart Fail Rev. 2020 Jan;25(1):85-91. doi: 10.1007/s10741-019-09810-4.

Abstract

Right ventricular function has long been neglected by heart failure specialists. We have now learnt that it is strongly associated with morbidity and mortality in all patients with heart failure, regardless of the degree of left ventricular dysfunction. Importantly, right ventricular function is tightly linked with pulmonary hypertension, and only a thorough understanding of how the right ventricle couples with the pulmonary circulation can provide an improved knowledge of the pathophysiology and possibly a more efficient treatment and a better prognosis in patients with heart failure.

Keywords: Heart failure; Pulmonary hypertension; Right ventricle.

Publication types

  • Review

MeSH terms

  • Heart Failure / etiology
  • Heart Failure / physiopathology*
  • Humans
  • Hypertension, Pulmonary / complications
  • Hypertension, Pulmonary / physiopathology*
  • Prognosis
  • Stroke Volume*
  • Ventricular Dysfunction, Right / complications
  • Ventricular Dysfunction, Right / physiopathology*
  • Ventricular Function, Left
  • Ventricular Remodeling*