Eyelid laxity and sleep apnea syndrome: a review

Rom J Ophthalmol. 2019 Jan-Mar;63(1):2-9.


The purpose of this paper is to review the association between a medical entity called the floppy eyelid syndrome (FES) and a very serious respiratory disease with repercussions on various other body organs and systems: the obstructive sleep apnea syndrome. The epidemiology, pathophysiology, and treatment of these two diseases are intertwined but still not enough recognized. Eye disorders affect a great number of patients in modern societies and the cause of their suffering is often left undiscovered, practitioners preferring a symptomatic treatment. However, the ophthalmologist should be aware of the possibility of a sleep disorder in their patients with certain pathologies, as well as sleep physicians, who should be aware of the possibility of eye problems and refer them for a checkup. Finally, a review of literature is undergone, evaluating the possibility that the treatment of one or the other disease may benefit both.

Keywords: floppy eyelid syndrome; sleep apnea syndrome.

Publication types

  • Review

MeSH terms

  • Eyelid Diseases / diagnosis
  • Eyelid Diseases / epidemiology
  • Eyelid Diseases / etiology*
  • Global Health
  • Humans
  • Incidence
  • Polysomnography
  • Risk Factors
  • Sleep Apnea Syndromes / complications*
  • Sleep Apnea Syndromes / diagnosis
  • Syndrome
  • Tears / metabolism