Oral Narrow-Spectrum Antibiotics for the Treatment of Urinary Tract Infection in Infants Younger Than 60 Days

Marisol Fernandez; Kathyrn Givens Merkel; Julio D Ortiz; Rachel Downey Quick

doi:10.1093/jpids/piz037

Oral Narrow-Spectrum Antibiotics for the Treatment of Urinary Tract Infection in Infants Younger Than 60 Days

J Pediatric Infect Dis Soc. 2020 Jul 13;9(3):378-381. doi: 10.1093/jpids/piz037.

Authors

Marisol Fernandez¹, Kathyrn Givens Merkel², Julio D Ortiz³, Rachel Downey Quick⁴

Affiliations

¹ Pediatric Infectious Diseases, University of Texas at Austin Dell Medical School, Dell Children's Medical Center of Central Texas.
² Department of Pharmacy, St David's South Austin Medical Center, Texas.
³ Department of Pediatrics, University of Texas at Austin Dell Medical School.
⁴ Pediatric Infectious Diseases, Dell Children's Medical Center of Central Texas, Austin.

PMID: 31199469
DOI: 10.1093/jpids/piz037

Abstract

Data on the outcome of infants younger than 60 days treated with a combination of intravenous and oral antibiotics for urinary tract infection are limited. This study examined susceptibility and successful outcomes of treatment with narrow-spectrum oral antibiotics. In addition, we describe the effects of antimicrobial stewardship education intervention on prescribing practices.

Keywords: antibiotics; bacteremia; infants; neonatal fever; urinary tract infection.

© The Author(s) 2019. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Publication types

Comparative Study

MeSH terms

Administration, Intravenous
Administration, Oral
Anti-Bacterial Agents / administration & dosage*
Antimicrobial Stewardship
Bacteremia / complications
Bacteremia / drug therapy
Enterobacteriaceae Infections / drug therapy*
Escherichia coli
Female
Fever / etiology
Humans
Infant
Infant, Newborn
Klebsiella pneumoniae
Male
Patient Readmission / statistics & numerical data
Recurrence
Retrospective Studies
Urinary Tract Infections / complications
Urinary Tract Infections / drug therapy*

Substances

Anti-Bacterial Agents