A case report of successful eradication of new isolates of Burkholderia cenocepacia in a child with cystic fibrosis

Abstract

Chronic respiratory infection with Burkholderia cenocepacia (Bc) in patients with cystic fibrosis (CF) is associated with accelerated decline in lung function and increased mortality. It is therefore important to attempt to eradicate new isolates, especially in children. However, there are no standardized guidelines to eradicate Bc. We report a case of successful eradication of new isolates of Bc in a 2-year-old child with CF using a combination of IV, nebulized antibiotics and sinus surgery.

Keywords: Burkholderia cenocepacia; cystic fibrosis; sinus surgery.