Repeated Detection of Carbapenemase-Producing Escherichia coli in Gulls Inhabiting Alaska

Antimicrob Agents Chemother. 2019 Jul 25;63(8):e00758-19. doi: 10.1128/AAC.00758-19. Print 2019 Aug.

Abstract

Here, we report the first detection of carbapenemase-producing Escherichia coli in Alaska and in wildlife in the United States. Wild bird (gull) feces sampled at three locations in Southcentral Alaska yielded isolates that harbored plasmid-encoded blaKPC-2 or chromosomally encoded blaOXA-48 and genes associated with antimicrobial resistance to up to eight antibiotic classes.

Keywords: carbapenemase-producing Enterobacteriaceae; multidrug resistance; whole-genome sequencing; wild birds.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Alaska
  • Animals
  • Bacterial Proteins / metabolism*
  • Birds / microbiology*
  • Carbapenem-Resistant Enterobacteriaceae / enzymology
  • Carbapenem-Resistant Enterobacteriaceae / genetics
  • Enterobacteriaceae / enzymology
  • Enterobacteriaceae / genetics
  • Escherichia coli / enzymology*
  • Escherichia coli / genetics*
  • Plasmids / genetics
  • beta-Lactamases / metabolism*

Substances

  • Bacterial Proteins
  • beta-Lactamases
  • carbapenemase