The accuracy of effect-size estimates under normals and contaminated normals in meta-analysis

Heliyon. 2019 Jun 11;5(6):e01838. doi: 10.1016/j.heliyon.2019.e01838. eCollection 2019 Jun.

Abstract

This article evaluates the accuracy of effect-size estimates for some estimation procedures in meta-analysis. The dilemma of which effect-size estimate is suitable is still a problem in meta-analysis. Monte Carlo simulations were used to generate random variables from a normal distribution or contaminated normal distribution for primary studies. The primary studies were hypothesised to have equal variance under different population effect sizes. The primary studies were also hypothesised to have unequal variance. Meta-analysis was done on the simulated hypothesized-primary-studies. The effect sizes for the simulated design of the primary studies were estimated using Cohen's d, Hedges' g, Glass' △, Cliff's delta d and the Probability of Superiority. Their corresponding standard error and confidence interval were computed and a comparison of an efficient estimator was done using statistical bias, percentage error and confidence interval width. The statistical bias, percentage error and confidence interval width pointed to Probability of Superiority as an accurate effect size estimate under contaminated normal distribution, and Hedges' g as the most accurate effect size estimates compared to Cohen's d and Glass' △ when equal variance assumptions are violated. This study suggests that the accuracy of effect size estimates depends on the details of the primary studies included in the meta-analysis.

Keywords: Accuracy; Applied mathematics; Effects size; Experimental design; Meta-analysis; Monte Carlo simulation; Statistical bias; Statistics.