A CRISPR Way to Identify Cancer Targets

N Engl J Med. 2019 Jun 20;380(25):2475-2477. doi: 10.1056/NEJMcibr1905048.
No abstract available

MeSH terms

  • CRISPR-Cas Systems
  • Cell Line, Tumor
  • Clustered Regularly Interspaced Short Palindromic Repeats*
  • Gene Expression Profiling
  • Gene Silencing*
  • Genetic Profile*
  • Humans
  • Loss of Function Mutation*
  • Microsatellite Instability
  • Neoplasms / genetics*
  • Precision Medicine
  • Werner Syndrome Helicase / genetics
  • Werner Syndrome Helicase / metabolism

Substances

  • Werner Syndrome Helicase