Mosquitocidal Chips Containing the Insect Growth Regulator Pyriproxyfen for Control of Aedes aegypti (Diptera: Culicidae)

Int J Environ Res Public Health. 2019 Jun 18;16(12):2152. doi: 10.3390/ijerph16122152.


Aedes aegypti were exposed to water treated with mosquitocidal chips containing the insecticide pyriproxyfen in a polymer formulation. Chips were tested under different conditions; different water volumes, in containers made of different material, and in water with different levels of organic matter. Treated chips caused 100% mortality of Ae. aegypti during their pupal stage independent of size or type of container, and the mount of organic matter contained in the water to which the mosquito larvae were exposed. When mosquitocidal chips were used in >25% of the oviposition containers within their cages, there was a significant control of the mosquito populations. Mosquitocidal chips worked in different environments, caused significant mosquito population decreases, and were effective in controlling Ae. aegypti.

Keywords: Aedes aegypti; Culicidae; Diptera; Insect Growth Regulator; Mosquito; Pyriproxyfen.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Aedes / drug effects*
  • Aedes / physiology
  • Animals
  • Female
  • Insecticides / toxicity*
  • Juvenile Hormones / toxicity*
  • Larva / drug effects
  • Larva / physiology
  • Mosquito Control
  • Oviposition / drug effects
  • Pyridines / toxicity*


  • Insecticides
  • Juvenile Hormones
  • Pyridines
  • pyriproxyfen