Negative MR4·0 chronic myeloid leukaemia and its possible implications for treatment-free remission

Br J Haematol. 2019 Sep;186(6):e181-e184. doi: 10.1111/bjh.16058. Epub 2019 Jun 19.
No abstract available

Keywords: MR4·0 negative; chronic myeloid leukaemia; molecular response level; qRT-PCR; treatment-free remission.

Publication types

  • Letter

MeSH terms

  • Female
  • Fusion Proteins, bcr-abl / blood*
  • Fusion Proteins, bcr-abl / genetics
  • Glucuronidase / blood*
  • Glucuronidase / genetics
  • Humans
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / blood*
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / therapy
  • Male
  • Neoplasm, Residual
  • Proto-Oncogene Proteins c-abl / blood*
  • Proto-Oncogene Proteins c-abl / genetics
  • RNA, Messenger / blood*
  • RNA, Messenger / genetics
  • RNA, Neoplasm / blood*
  • RNA, Neoplasm / genetics
  • Remission Induction*

Substances

  • RNA, Messenger
  • RNA, Neoplasm
  • ABL1 protein, human
  • Fusion Proteins, bcr-abl
  • Proto-Oncogene Proteins c-abl
  • Glucuronidase