The nature of human IL-6

J Exp Med. 2019 Sep 2;216(9):1969-1971. doi: 10.1084/jem.20191002. Epub 2019 Jun 24.

Abstract

Countless functions have been attributed experimentally to IL-6. In this issue of JEM, Spencer et al. (https://doi.org/10.1084/jem.20190344) reveal essential, nonredundant functions of human IL-6. Patients with genetic deficiencies of the IL-6 receptor suffer from "hyper IgE syndrome."

Publication types

  • Comment

MeSH terms

  • Humans
  • Interleukin-6*
  • Receptors, Interleukin-6*

Substances

  • Interleukin-6
  • Receptors, Interleukin-6