Radiation-induced cutaneous angiosarcoma of the abdomen in a patient with cervical cancer: A case report

J Obstet Gynaecol Res. 2019 Sep;45(9):1941-1943. doi: 10.1111/jog.14034. Epub 2019 Jun 25.

Abstract

Cutaneous angiosarcoma (CA) is a rare and aggressive malignant tumor that develops from vascular endothelium. Secondary CAs are often caused by radiotherapy and chronic lymphedema. Most radiation-induced CAs are associated with breast or gynecologic cancer. The prognosis of CA is extremely poor, with a 5-year survival rate ranging from 12% to 34%. Therapeutic options are limited, and surgical excision with negative margins remains the mainstay of treatment. We report a case of a 63-year-old woman who developed secondary CA at an irradiated site 7 years after receiving radiotherapy for cervical cancer.

Keywords: angiosarcoma; cervical cancer; radiotherapy.

Publication types

  • Case Reports

MeSH terms

  • Abdomen
  • Female
  • Hemangiosarcoma / etiology
  • Hemangiosarcoma / pathology*
  • Humans
  • Middle Aged
  • Neoplasms, Radiation-Induced / etiology
  • Neoplasms, Radiation-Induced / pathology*
  • Skin Neoplasms / etiology
  • Skin Neoplasms / pathology*
  • Uterine Cervical Neoplasms / radiotherapy*