Immune-mediated tuberculous uveitis - A rare association with papulonecrotic tuberculid

Indian J Ophthalmol. 2019 Jul;67(7):1207-1209. doi: 10.4103/ijo.IJO_1550_18.


The tuberculids are a group of distinct clinicopathological form of skin lesions representing hypersensitivity reaction to hematogenous dissemination of Mycobacterium tuberculosis or its antigen from an underlying active or a silent focus of tuberculosis elsewhere in the body in an individual with a strong antituberculous cell-mediated immunity and by definition do not show bacilli on special stains and are culture-negative. Ocular involvement can occur in tuberculosis, both due to direct invasion by the bacilli as well as an immune-mediated reaction; however, immune-mediated tuberculous uveitis occurring as a hypersensitivity response in association with PNT has hardly been reported in the literature. Here we report one such rare case.

Keywords: Rare association; tuberculids; tuberculous uveitis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antigens, Bacterial / immunology*
  • Biopsy
  • Eye Infections, Bacterial / diagnosis
  • Eye Infections, Bacterial / etiology
  • Eye Infections, Bacterial / immunology*
  • Humans
  • Male
  • Mycobacterium tuberculosis / immunology*
  • Mycobacterium tuberculosis / isolation & purification
  • Necrosis
  • Skin / microbiology
  • Skin / pathology*
  • Tuberculosis, Cutaneous / complications*
  • Tuberculosis, Cutaneous / diagnosis
  • Tuberculosis, Ocular / diagnosis
  • Tuberculosis, Ocular / etiology
  • Tuberculosis, Ocular / immunology*
  • Uveitis / diagnosis
  • Uveitis / etiology
  • Uveitis / immunology*


  • Antigens, Bacterial