Overall Results for a National Program of Photodynamic Therapy for Basal Cell Carcinoma: A Multicenter Clinical Study to Bring New Techniques to Social Health Care

Cancer Control. 2019 Jan-Dec;26(1):1073274819856885. doi: 10.1177/1073274819856885.

Abstract

Along the past years, a national program to implement photodynamic therapy (PDT) for nonmelanoma skin cancer (NMSC) was performed over the Brazilian territory. Using a strategy involving companies, national bank, and medical partners, equipment, medication, and protocols were tested in a multicenter study. With results collected over 6 years, we could reach a great deal of advances concerning the use of PDT for skin cancer. We present the overall reached results of the program and discuss several aspects about it, including public politics of treatment. A discussion about advantages of this technique within conditions of health care is placed, comparing PDT with surgery, including an analysis about the implementation of PDT in countries in development as Brazil, considering not only technical but social aspects, as the distribution of medical doctor in the Brazilian territory. The program resulted in a huge dissemination of PDT in Brazil and many countries in Latin America, in a partnership among public politics, universities, companies, and hospitals and clinics and in the insertion of national technologies as option to treat NMSC. Consequence of the program is mainly the continuation of the use of PDT in Brazil and many countries in Latin America.

Keywords: BCC; PDT; basal cell carcinoma; nonmelanoma skin cancer; photodynamic therapy.

Publication types

  • Clinical Trial
  • Multicenter Study

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Basal Cell Carcinoma / drug therapy*
  • Basal Cell Carcinoma / epidemiology
  • Brazil / epidemiology
  • Female
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • National Health Programs*
  • Photochemotherapy*
  • Program Evaluation*
  • Skin Neoplasms / drug therapy*
  • Skin Neoplasms / epidemiology
  • Treatment Outcome
  • Young Adult