Mass-scale red cell genotyping of blood donors: from data visualization to historical antigen labeling and donor recruitment

Transfusion. 2019 Sep;59(9):2768-2770. doi: 10.1111/trf.15419. Epub 2019 Jun 27.

Abstract

Donor red cell genotyping provides efficiencies to identify "in demand" blood donors for transfusion recipients requiring antigen-negative blood. Donor red cell genotype information can be used to label units with historical types and introduced throughout the supply chain from the blood center to the hospital transfusion service and has potential to be used in recruitment strategies.

Publication types

  • Review

MeSH terms

  • Blood Donors*
  • Blood Group Antigens / analysis
  • Blood Group Antigens / metabolism
  • Blood Grouping and Crossmatching / methods
  • Blood Grouping and Crossmatching / standards
  • Blood Transfusion / methods
  • Blood Transfusion / standards
  • Data Visualization*
  • Donor Selection / methods*
  • Donor Selection / standards
  • Erythrocytes / chemistry
  • Erythrocytes / metabolism*
  • Genotype
  • Genotyping Techniques / methods
  • High-Throughput Screening Assays / methods*
  • High-Throughput Screening Assays / standards
  • Humans
  • Mass Screening / methods
  • Mass Screening / standards
  • Polymorphism, Single Nucleotide
  • Product Labeling* / methods
  • Product Labeling* / standards

Substances

  • Blood Group Antigens