[Efficacy of sodium thiosulphate in a case of calciphylaxis in a chronic nephropathic ninety-year-old patient on conservative therapy]

G Ital Nefrol. 2019 Jun 11;36(3):2019-vol3.
[Article in Italian]

Abstract

Calcific uremic arteriolopathy, also known as calciphylaxis (CUA), is a rare and potentially fatal condition that occurs in 1-4% of the population with chronic renal failure, most often on dialysis treatment. The pathogenesis is not yet clear although several hypotheses have been advanced, most importantly the alteration of the calcium phosphorus metabolism. Administration of sodium thiosulfate (STS) is the emerging therapy. Below, we report the case of an elderly chronic kidney patient on conservative therapy suffering from CUA who has been successfully treated with STS.

Keywords: calciphylaxis; chronic kidney disease; sodium thiosulfate.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Calciphylaxis / complications
  • Calciphylaxis / drug therapy*
  • Conservative Treatment
  • Female
  • Humans
  • Kidney Failure, Chronic / complications
  • Kidney Failure, Chronic / therapy
  • Thiosulfates / therapeutic use*
  • Treatment Outcome

Substances

  • Thiosulfates
  • sodium thiosulfate