Quantum dots from microfluidics for nanomedical application

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2019 Sep;11(5):e1567. doi: 10.1002/wnan.1567. Epub 2019 Jul 1.

Abstract

Nanomedicine, with its advantages of rapid diagnosis, high sensitivity and high accuracy, has aroused extensive interest of researchers, as the cornerstone of nanomedicine, nanomaterials achieve extra attention and rapid development. Among nanomaterials, quantum dots stand out due to their long fluorescence lifetime and excellent antiphotobleaching performance. At present, quantum dots have been applied to the diagnosis and treatment of diseases and various strategies have been presented to fabricate quantum dots. Microfluidic is one promising strategy since microfluidic device can provide an effective platform for the diagnosis of trace disease markers. In this paper, research progress in the microfluidic synthesis of quantum dots and quantum dot-based nanomedical application is discussed. The classification of quantum dots is firstly introduced, and the researches on quantum dots synthesis based on microfluidic is then mainly described, including the sort, design, preparation of microfluidic synthesis device and its application in synthesis. Nanomedical applications of the quantum dots is especially described and emphasized. The prospects for future development of quantum dots from microfluidic for nanomedical application are finally presented. This article is categorized under: Diagnostic Tools > in vitro Nanoparticle-Based Sensing.

Keywords: biomedical application; microfluidic; nanomedicine; quantum dot.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biomedical Technology
  • Biosensing Techniques
  • Drug Delivery Systems
  • Humans
  • Microfluidics*
  • Nanomedicine*
  • Quantum Dots / chemistry*