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Review
. 2019 Jul 2;24(13):2436.
doi: 10.3390/molecules24132436.

Gastrodia elata Blume Polysaccharides: A Review of Their Acquisition, Analysis, Modification, and Pharmacological Activities

Haodong Zhu  1   2   3 , Chen Liu  2   3   4 , Jinjun Hou  2   3 , Huali Long  2   3 , Bing Wang  2   3 , De'an Guo  2   3 , Min Lei  5   6 , Wanying Wu  7   8
Affiliations
Review

Gastrodia elata Blume Polysaccharides: A Review of Their Acquisition, Analysis, Modification, and Pharmacological Activities

Haodong Zhu et al. Molecules. .

Abstract

Gastrodia elata Blume (G. elata) is a valuable Traditional Chinese Medicine (TCM) with a wide range of clinical applications. G. elata polysaccharides, as one of the main active ingredients of G. elata, have interesting extraction, purification, qualitative analysis, quantitative analysis, derivatization, and pharmacological activity aspects, yet a review of G. elata polysaccharides has not yet been published. Based on this, this article summarizes the progress of G. elata polysaccharides in terms of the above aspects to provide a basis for their further research and development.

Keywords: Gastrodia elata Bl (G. elata); pharmacological action; phytochemistry; polysaccharides.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Chemical structure of part of the polysaccharides derived from G. elata: x + y = R; 1. AGEW: R = 14; 2. WTMA: R = 15; 3. WGEW: R = 16; and 4. PGEB-3H: R = 20 [5].
Figure 2
Figure 2
Structures of WGEW (a) and its sulfated derivatives WSS25 and WSS45 (b) [4].
Figure 3
Figure 3
The pathway of tube formation suppression by the sulfated polysaccharides WSS25 from G. elata.
See this image and copyright information in PMC

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