Molecular epidemiology of Giardia and Cryptosporidium infections - What's new?

R C A Thompson; A Ash

doi:10.1016/j.meegid.2019.103951

Molecular epidemiology of Giardia and Cryptosporidium infections - What's new?

Infect Genet Evol. 2019 Nov:75:103951. doi: 10.1016/j.meegid.2019.103951. Epub 2019 Jul 4.

Authors

R C A Thompson¹, A Ash²

Affiliations

¹ School of Veterinary and Life Sciences, Murdoch University, Murdoch, WA 6150, Australia. Electronic address: a.thompson@murdoch.edu.au.
² School of Veterinary and Life Sciences, Murdoch University, Murdoch, WA 6150, Australia.

PMID: 31279819
DOI: 10.1016/j.meegid.2019.103951

Abstract

New information generated since 2016 from the application of molecular tools to infections with Giardia and Cryptosporidium is critically summarised. In the context of molecular epidemiology, nomenclature, taxonomy, in vitro culture, detection, zoonoses, population genetics and pathogenicity, are covered. Whole genome sequencing has had the greatest impact in the last three years. Future advances will provide a much better understanding of the zoonotic potential of both parasites, their diversity and how this is linked to pathogenesis in different hosts.

Keywords: Cryptosporidium; Detection; Giardia; Molecular epidemiology; Pathogenicity; Taxonomy; Wildlife; Zoonoses.

Publication types

Review

MeSH terms

Animals
Animals, Wild
Cryptosporidiosis / epidemiology*
Cryptosporidiosis / genetics*
Giardiasis / epidemiology*
Giardiasis / genetics*
Humans
Molecular Epidemiology*