Platelet-Rich Plasma for Skin Rejuvenation: Facts, Fiction, and Pearls for Practice

Facial Plast Surg Clin North Am. 2019 Aug;27(3):405-411. doi: 10.1016/j.fsc.2019.04.006.


Platelet-rich plasma (PRP) has gained popularity in facial plastic surgery because of its role in wound healing. PRP, having a higher concentration of platelets, allows for greater release of growth factors and biologically active proteins, which in turn activates the wound-healing cascade stimulating neoangiogenesis and collagen production. One of the most popular uses for PRP is for facial skin rejuvenation in the form of dermal injections and topical application during microneedling. The promising nature of PRP makes using it for injection and/or in conjunction with microneedling a good addition to any practice that deals with skin rejuvenation.

Keywords: Acne scars; Collagen induction; Facial rejuvenation; Microneedling; Platelet gel; Platelet-rich plasma; Skin rejuvenation; Wrinkles.

Publication types

  • Review

MeSH terms

  • Cosmetic Techniques*
  • Humans
  • Platelet-Rich Plasma*
  • Rejuvenation*
  • Skin Aging*