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Review
, 7 (3)

The Limits Between Bipolar Disorder and Borderline Personality Disorder: A Review of the Evidence

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Review

The Limits Between Bipolar Disorder and Borderline Personality Disorder: A Review of the Evidence

Marsal Sanches. Diseases.

Abstract

Bipolar disorder and borderline personality disorder are among the most frequently diagnosed psychiatric conditions. However, the nosological aspects and diagnostic boundaries of both conditions have historically been the object of considerable controversy. The present paper critically analyzes this debate, in light of available evidence. Clinical and neurobiological differences between bipolar disorder and borderline personality disorder are discussed, as well as the factors possibly involved in the overlap between both conditions and the potential implications of this.

Keywords: bipolar disorder; borderline personality disorder; diagnosis; neuroimaging.

Conflict of interest statement

The author declares no conflict of interest.

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References

    1. Sanches M., Soares J.C. New drugs for bipolar disorder. Curr. Psychiatry Rep. 2011;13:513–521. doi: 10.1007/s11920-011-0231-1. - DOI - PubMed
    1. Ansell E.B., Sanislow C.A., McGlashan T.H., Grilo C.M. Psychosocial impairment and treatment utilization by patients with borderline personality disorder, other personality disorders, mood and anxiety disorders, and a healthy comparison group. Compr. Psychiatry. 2007;48:329–336. doi: 10.1016/j.comppsych.2007.02.001. - DOI - PubMed
    1. Temes C.M., Frankenburg F.R., Fitzmaurice G.M., Zanarini M.C. Deaths by suicide and other causes among patients with borderline personality disorder and personality-disordered comparison subjects over 24 years of prospective follow-up. J. Clin. Psychiatry. 2019;80 doi: 10.4088/JCP.18m12436. - DOI - PubMed
    1. Sanches M. Bipolar disorder: How to avoid overdiagnosis. Curr. Psychiatry. 2018;17:29.
    1. Kroll J., Sines L., Martin K., Lari S., Pyle R., Zander J. Borderline personality disorder. Construct validity of the concept. Arch. Gen. Psychiatry. 1981;38:1021–1026. doi: 10.1001/archpsyc.1981.01780340073009. - DOI - PubMed
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