Buprenorphine for Opioid Use Disorder: A Review of Comparative Clinical Effectiveness, Safety, Cost-Effectiveness, and Guidelines [Internet]

Excerpt

CADTH has previously reviewed the evidence for the use of buprenorphine formulations for the treatment of opioid use disorders (OUDs). One report was limited to pregnant populations, another was a qualitative review of patient preferences and perspectives, and the third was a summary of abstracts based on evidence available in 2017. The objective of the current report is to evaluate the comparative clinical effectiveness, safety, cost-effectiveness and evidencebased guidelines regarding various buprenorphine or combination product of buprenorphine with naloxone (BUP-NAL) formulations for the treatment of OUD.