Heritable variation at the chromosome 21 gene ERG is associated with acute lymphoblastic leukemia risk in children with and without Down syndrome

Leukemia. 2019 Nov;33(11):2746-2751. doi: 10.1038/s41375-019-0514-9. Epub 2019 Jul 11.
No abstract available

Publication types

  • Letter
  • Meta-Analysis
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • California / epidemiology
  • California / ethnology
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Chromosomes, Human, Pair 21 / genetics
  • Down Syndrome / complications
  • Down Syndrome / ethnology
  • Down Syndrome / genetics*
  • Female
  • Genetic Predisposition to Disease
  • Genome-Wide Association Study
  • Guatemala / epidemiology
  • Guatemala / ethnology
  • Haplotypes
  • Hispanic Americans
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Polymorphism, Single Nucleotide*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / ethnology
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Principal Component Analysis
  • Risk Factors
  • Transcriptional Regulator ERG / genetics

Substances

  • ERG protein, human
  • Transcriptional Regulator ERG