Noninvasive Sweat-Lactate Biosensor Emplsoying a Hydrogel-Based Touch Pad

Sci Rep. 2019 Jul 12;9(1):10102. doi: 10.1038/s41598-019-46611-z.


This study is the first report demonstrating proof-of-concept for a hydrogel-based touch sensor pad used for the non-invasive extraction and detection of sweat components. The sensor device was composed of an electrochemical L-lactate biosensor covered with an agarose gel in a phosphate buffer saline. When human skin contacts the agarose gel, L-lactate in sweat was continuously extracted into the gel, followed by in-situ potentiometric detection without controlled conditions. This novel type of sweat sensor is expected to enable the simple, non-invasive daily periodic monitoring of sweat biomarkers for advanced personal healthcare methods in the future.

Publication types

  • Research Support, Non-U.S. Gov't