Specifications of Standards in Systems and Synthetic Biology: Status and Developments in 2019

J Integr Bioinform. 2019 Jul 13;16(2):20190035. doi: 10.1515/jib-2019-0035.


This special issue of the Journal of Integrative Bioinformatics presents an overview of COMBINE standards and their latest specifications. The standards cover representation formats for computational modeling in synthetic and systems biology and include BioPAX, CellML, NeuroML, SBML, SBGN, SBOL and SED-ML. The articles in this issue contain updated specifications of SBGN Process Description Level 1 Version 2, SBML Level 3 Core Version 2 Release 2, SBOL Version 2.3.0, and SBOL Visual Version 2.1.

Publication types

  • Review

MeSH terms

  • Computer Simulation*
  • Models, Biological*
  • Programming Languages*
  • Synthetic Biology*
  • Systems Biology*