The tyrosinase-positive oculocutaneous albinism locus is not linked to the beta-globin locus in man

Hum Genet. 1988 May;79(1):89. doi: 10.1007/BF00291719.


Twenty informative families have been studied. and linkage between the tyrosinase-positive oculocutaneous albinism locus and the beta-globin locus has been excluded with a maximum lod score of -9.85 at 0 = 0.05. In lower mammals there is linkage between the p locus (considered to be equivalent to the human tyrosinase-positive oculocutaneous albinism) and the beta-globin locus.

MeSH terms

  • Albinism / enzymology
  • Albinism / genetics*
  • Catechol Oxidase / genetics*
  • Female
  • Genetic Linkage*
  • Globins / genetics*
  • Humans
  • Male
  • Monophenol Monooxygenase / genetics*


  • Globins
  • Catechol Oxidase
  • Monophenol Monooxygenase