Evolutionary trends in the prevalence of anti-HDV antibodies among patients positive for HBsAg referred to a national laboratory in Cameroon from 2012 to 2017

BMC Res Notes. 2019 Jul 15;12(1):417. doi: 10.1186/s13104-019-4460-4.

Abstract

Objective: The aim of this study was to update the data on the prevalence of anti-HDV antibodies in Cameroon.

Results: Antibodies against hepatitis Delta virus (Anti-HDV) were found in 16.48% (95% CI 11.46-18.77%) of 426 hepatitis B virus surface antigen positive patients in Cameroon. Remarkably, they were significantly higher among people over 40 years and those living in the East and South regions of Cameroon at 66.7%, 50%, and 40%, respectively. These results suggest that older age and living in areas in the dense forest may be risk factors for Hepatitis D infection.

Keywords: Anti-HDV antibodies; Cameroon; HBsAg; Prevalence; Trends.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Biological Evolution
  • Cameroon / epidemiology
  • Child
  • Cross-Sectional Studies
  • Female
  • Hepatitis Antibodies / immunology*
  • Hepatitis B / diagnosis*
  • Hepatitis B / epidemiology
  • Hepatitis B / virology
  • Hepatitis B Surface Antigens / immunology*
  • Hepatitis D / diagnosis*
  • Hepatitis D / epidemiology
  • Hepatitis D / virology
  • Hepatitis Delta Virus / immunology*
  • Hepatitis Delta Virus / physiology
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Young Adult

Substances

  • Hepatitis Antibodies
  • Hepatitis B Surface Antigens