Inkjet-Printed Colorimetric Paper-Based Gas Sensor Arrays for the Discrimination of Volatile Primary Amines with Amine-Responsive Dye-Encapsulating Polymer Nanoparticles

Methods Mol Biol. 2019:2027:101-114. doi: 10.1007/978-1-4939-9616-2_9.

Abstract

Arrays of gas sensors are of high interest for "electronic nose" applications. Here, we describe the fabrication of a colorimetric single-use gas sensor array made of paper allowing the discrimination of volatile primary amines based on their polarity. For this purpose, polymeric nanoparticles with different polarities containing an amine-sensitive chromogenic dye are deposited onto paper substrates by means of inkjet printing. Data processing is conducted by red-green-blue (RGB) color extraction, followed by principal component analysis (PCA) or agglomerative hierarchical clustering (AHC) analysis. The application to the discrimination of two cheese samples is demonstrated.

Keywords: Agglomerative hierarchical clustering; Colorimetric gas sensor array; Dye-encapsulating polymer nanoparticles; Inkjet-printing; Paper-based analytical devices; Principal component analysis; Volatile primary amines.

MeSH terms

  • Amines / analysis*
  • Amines / chemistry
  • Cheese / analysis
  • Cluster Analysis
  • Color
  • Colorimetry / instrumentation*
  • Colorimetry / methods
  • Coloring Agents / chemistry
  • Electronic Nose*
  • Gases / analysis*
  • Models, Chemical
  • Nanoparticles / chemistry
  • Polymers / chemistry
  • Principal Component Analysis
  • Printing
  • Volatile Organic Compounds / analysis*
  • Volatile Organic Compounds / chemistry

Substances

  • Amines
  • Coloring Agents
  • Gases
  • Polymers
  • Volatile Organic Compounds