No Evidence for Role of Cutavirus in Malignant Melanoma

Emerg Infect Dis. 2019 Aug;25(8):1600-16002. doi: 10.3201/eid2508.190096.

Abstract

Cutavirus was previously found in cutaneous melanoma. We detected cutavirus DNA in only 2/185 melanoma biopsies and in 0/52 melanoma metastases from patients in Germany. Viral DNA was localized in the upper epidermal layers. Swab specimens from healthy skin were cutavirus positive for 3.8% (9/237) of immunocompetent and 17.1% (35/205) of HIV-positive men.

Keywords: Germany; cutaneous; cutavirus; melanoma; parvovirus; skin; viruses.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biopsy
  • DNA, Viral
  • Germany / epidemiology
  • Humans
  • Melanoma / diagnosis
  • Melanoma / epidemiology*
  • Melanoma / etiology*
  • Neoplasm Staging
  • Parvoviridae Infections / complications*
  • Parvoviridae Infections / virology
  • Parvovirus*
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / epidemiology
  • Skin Neoplasms / etiology
  • Viral Load

Substances

  • DNA, Viral

Supplementary concepts

  • Melanoma, Cutaneous Malignant