Novel Virus Related to Kaposi's Sarcoma-Associated Herpesvirus from Colobus Monkey

Emerg Infect Dis. 2019 Aug;25(8):1548-1551. doi: 10.3201/eid2508.181802.


We determined the complete genome sequence of a virus isolated from a mantled guereza that died of primary effusion lymphoma. The virus is closely related to Kaposi's sarcoma-associated herpesvirus (KSHV) but lacks some genes implicated in KSHV pathogenesis. This finding may help determine how KSHV causes primary effusion lymphoma in humans.

Keywords: Germany; Kaposi sarcoma; Kaposi’s sarcoma–associated herpesvirus; Virology; bioinformatics; colobine gammaherpesvirus 1; evolution; herpesvirus; macaque; monkey; viruses.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biopsy
  • Colobus
  • Genome, Viral
  • Genomics
  • Herpesvirus 8, Human / classification*
  • Herpesvirus 8, Human / genetics*
  • Herpesvirus 8, Human / isolation & purification
  • Immunohistochemistry
  • Lymphoma / veterinary*
  • Male
  • Monkey Diseases / diagnosis*
  • Monkey Diseases / epidemiology
  • Monkey Diseases / virology*
  • Phylogeny
  • Whole Genome Sequencing