Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2019 Aug 8;49(4):1033-1040.
doi: 10.3906/sag-1810-204.

Effect of 4 Weeks of Frankincense Consumption on Explicit Motor Memory and Serum BDNF in Elderly Men

Free PMC article
Randomized Controlled Trial

Effect of 4 Weeks of Frankincense Consumption on Explicit Motor Memory and Serum BDNF in Elderly Men

Elham Asadı et al. Turk J Med Sci. .
Free PMC article


Background/aim: Memory is a mechanism for coding, storing, and recalling information. Weak memory and learning disability are common psychological problems in the elderly. The aim of this study was to investigate the effect of 4 weeks of frankincense consumption on explicit motor memory and serum BDNF in the elderly.

Materials and methods: Twenty elderly men (mean age of 60.2 ± 1.7 years) were randomly divided into two groups: experimental (n = 12) and placebo (n = 8). The first blood samples were collected 24 h before the pretest. Then both groups participated in a 4-week exercise program based on the protocol of exercising motor memory. During this period, the experimental group received 500-mg frankincense pills two times a day. The second blood sample collection and acquisition test were conducted following the last session of the exercise program. A retention test and a third blood sampling were performed 2 weeks after the last training session. Mixed analysis of variance (2 × 3) for repeated measures was used to analyze the data.

Results: Intergroup comparisons showed that frankincense had a significant effect on the acquisition and retention of explicit motor memory. No difference was observed in serum BDNF between the experimental and placebo groups.

Conclusion: This study revealed that 4 weeks of frankincense consumption facilitates the acquisition and retention of motor memory in older men with moderate mental status.

Keywords: Frankincense; explicit motor memory; BDNF; elderly.

Conflict of interest statement


none declared

Similar articles

See all similar articles


    1. SharifzadehM Posttraining intrahippocampal infusion of a protein kinase AII inhibitor impairs spatial memory retention in rats. Journal of Neuroscience Research. 2005;79:392–400. - PubMed
    1. KantakSS Transfer of motor learning engages specific neural substrates during motor memory consolidation dependent on the practice structure. Journal of Motor Behavior. 2011;34:499–507. - PubMed
    1. VossJL Brain substrates of implicit and explicit memory: the importance of concurrently acquired neural signals of both memory types. Neuropsychologia. 2008;46:3021–3029. - PMC - PubMed
    1. FosterJK Glucose and memory: fractionation of enhancement effects. Psychopharmacology. 1990;137:259–270. - PubMed
    1. BrownTP Consolidating the effects of waking and sleep on motorsequence learning. J Neurosci. 2010;30:13977–13982. - PMC - PubMed

Publication types

LinkOut - more resources