Naturally Occurring Lumazines

J Nat Prod. 2019 Jul 26;82(7):2054-2065. doi: 10.1021/acs.jnatprod.9b00351. Epub 2019 Jul 18.


Natural products containing a lumazine motif were first isolated from natural sources in 1940. These natural products are relatively rare, with fewer than 100 lumazines known to occur in Nature. This review discusses the isolation of lumazines, their biological activity, and their biosynthesis, where known.

Publication types

  • Review

MeSH terms

  • Biological Products / chemistry
  • Molecular Structure
  • Pteridines / chemistry*
  • Pteridines / pharmacology*


  • Biological Products
  • Pteridines
  • lumazine