Spontaneous coronary artery dissection (SCAD) is a relatively rare cause of acute coronary syndrome compared with atherosclerotic plaque rupture and predominantly occurs in young women. SCAD is associated with various conditions, such as emotional stress, pregnancy, hormonal therapy, collagen diseases, fibromuscular dysplasia, or vasospasm. Long-term cardiovascular events are common including the recurrence of SCAD. We report a case of SCAD with de novo recurrence at only 4 days after the first attack. <Learning objectives: Spontaneous coronary artery dissection (SCAD) is a relatively rare cause of acute coronary syndrome (ACS) compared with atherosclerotic plaque rupture, but if young to middle-aged women develop ACS, a high suspicion of SCAD is warranted. Recurrence of SCAD is common with 4- to 10-year follow-up. However, SCAD recurred early as in our case.>.
Keywords: Acute coronary syndrome; De novo recurrence; Hormonal therapy; Spontaneous coronary artery dissection.