Reverse-engineering growth and form in Heidelberg

Development. 2019 Jul 19;146(14):dev177261. doi: 10.1242/dev.177261.

Abstract

The EMBO-EMBL Symposium 'Synthetic Morphogenesis: From Gene Circuits to Tissue Architecture' was held in Heidelberg, Germany, in March 2019, with 150 participants seeking to reverse-engineer embryogenesis, emphasizing quantitative simulation and the use of synthetic systems to test models. This highly dynamic, interdisciplinary mix of quantitative developmental genetics, bioengineering, synthetic biology and artificial life aimed to reveal how evolution exploits physical forces and genetics to implement the cell- and tissue-level decision-making required for complex morphogenesis.

Keywords: Cells; Developmental biology; Engineering; Genetics; Modeling; Synthetic biology.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Bioengineering / methods
  • Bioengineering / organization & administration*
  • Bioengineering / trends
  • Congresses as Topic* / organization & administration
  • Congresses as Topic* / standards
  • Developmental Biology / methods*
  • Developmental Biology / organization & administration
  • Developmental Biology / trends
  • Embryonic Development / physiology
  • Gene Regulatory Networks / physiology
  • Genetic Engineering* / methods
  • Genetic Engineering* / trends
  • Germany
  • Humans
  • Models, Biological
  • Morphogenesis / physiology
  • Synthetic Biology / methods
  • Synthetic Biology / organization & administration
  • Synthetic Biology / trends