Capgras' Delusion: A Systematic Review of 255 Published Cases

Psychopathology. 2019;52(3):161-173. doi: 10.1159/000500474. Epub 2019 Jul 19.

Abstract

Background: Capgras' delusion has captured psychiatrists' imaginations, but the clinical features of the delusion have rarely been studied and presented systematically.

Aims: The present study systematically reviews all case reports on Capgras' delusion in the English language in order to better understand differences between organic and functional aetiologies.

Methods: All medical and psychiatric databases were searched, as were the bibliographies of published case reports, narrative reviews, and book chapters.

Results: A total of 258 cases were identified from 175 papers. Functional Capgras' delusion was more associated with a wider variety of imposters; multiple imposters; other misidentification syndromes; auditory hallucinations; other delusions; and formal thought disorder. Organic cases were associated with age; inanimate objects; memory and visual-spatial impairments; right hemispheric dysfunction; and visual hallucinations. Executive dysfunction and aggression were associated with both types.

Conclusions: Specific features of the -Capgras' delusional content and associated signs point to either organic or functional aetiology. The delusion is more amorphous than many theorists have supposed, which challenges their explanatory models.

Keywords: Capgras’ syndrome; Cognitive neuropsychiatry; Misidentification syndrome; Organic syndromes; Psychotic disorders.

Publication types

  • Systematic Review

MeSH terms

  • Adult
  • Capgras Syndrome / diagnosis*
  • Delusions / psychology*
  • Female
  • Humans
  • Male
  • Middle Aged