Valve-in-Valve TAVR: State-of-the-Art Review

Innovations (Phila). 2019 Aug;14(4):299-310. doi: 10.1177/1556984519858020. Epub 2019 Jul 22.


An increasing number of surgically implanted bioprostheses will require re-intervention for structural valve deterioration. Valve-in-valve transcatheter aortic valve replacement (ViV TAVR) has become an alternative to reoperative surgery, currently approved for high-risk and inoperable patients. Challenges to the technique include higher rates of prosthesis-patient mismatch and coronary obstruction, compared to native valve TAVR. Herein, we review results of ViV TAVR and novel techniques to overcome the aforementioned challenges.

Keywords: aortic valve; bioprosthesis; transcatheter aortic valve replacement; valve-in-valve.

Publication types

  • Review

MeSH terms

  • Aortic Valve / surgery*
  • Aortic Valve Insufficiency / surgery*
  • Aortic Valve Stenosis / surgery*
  • Bioprosthesis*
  • Heart Valve Prosthesis Implantation
  • Heart Valve Prosthesis*
  • Humans
  • Postoperative Complications / surgery*
  • Prosthesis Failure*
  • Reoperation
  • Transcatheter Aortic Valve Replacement / methods*